Alick Osborne's daughter Jane Osborne married Brisbane Water Magistrate Alfred Holden at Illawarra in 1838.

His son Alick died in October 1842 age 21, and wife Anne died 15 October 1853 age 61 years.

Alick Osborne died in Omagh Irleand on 12th March 1856. The Empire carried his obituary:

He was the son of Archibald Osborne, Esq., of Dirnaseer, in the county of Tyrone. At an early age, he entered the Navy, in which service he remained as surgeon upwards of forty years. He then emigrated to New South Wales and settled in the district of Illawarra where two of his brothers, the late Dr. John Osborne, and the present member for East Camden  (Henry) also resided.

At the general election in 1851 Dr. Osborne, was elected member of the Legislative Council for the united counties of St. Vincent and Murray, after a sharp contest in which he was opposed by Charles Campbell Esq., In January 1855 he resigned his seat and proceeded to Europe.

In the council. Dr. Osborne was regular in his attendance and took an active interest in the discharge of his duties. His political views, which were frequently expressed in the debates, always briefly and pithily, were of a strong conservative cast. In maintaining his own opinions with out-spoken manliness, however, he never manifested disrespect towards others, meeting his opponents with fairness while preserving his fidelity to his friends. Dr. Osborne was sixty three years of age at his death.

  Notes on the Present State and Prospects of Society in the colony of NSW