Francis Little established the property 'Invermein' next to the property 'Satur' which was selected for his uncle William Bell Carlyle.  They were situated on the Dartbrook and near Kingdon Ponds. In the 1832 Directory the country in the district is described as undulating with soil similar to Twickenham Meadows.

Before reaching Invermein travellers first passed through the grant belonging to Dumaresq and the town of St. Aubin's and then two government reserves. Dr. Little's land was east of the grant taken by George Sparke. A mile from Francis Little's land the burning hill of Wingen,  could be found. The whole of the surrounding country was strewn with petrifactions and interesting geological specimens. Read Rev. Wilton's description of Mt. Wingen in 1831

Dr. Little married widow Mary Ann Fennell Bell, the 4th daughter of Archibald Bell of 'Belmont', at Windsor on 3rd August 1831. A son William and a daughter Sarah were born to Francis and Mary Ann in 1833 followed by Archibald in 1835.

Convicts assigned to Dr. Little in the 1820's and 1830's included Thomas Delmore per 'Phoenix', Edward Stewart per 'Phoenix' and Patrick Creighton per 'Phoenix,  William Brooke per 'Marquis of Hastings', Darby Carey per 'Hooghley', William Burnes per 'Countess of Harcourt', James Worthing per 'Surry, William Downes per 'Lady Harewood', James Osborne per 'Lady Harewood', Mary Collier ' Pyramus', John Kelly per 'Dunvegan Castle', Robert Baker per 'Eleanor', Charles Banks per 'Dunvegan Castle' and John Baugh per 'Asia'. Select HERE to find more convicts assigned to Francis Little at Invermein

Francis Little died 14th June 1860 aged 62 twenty five years after Mary Ann who died in 1835.